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Various

"Scientific American Supplement, No. 324, March 18, 1882"


Hyoscyamine crystallizes in the acicular form, with greater difficulty
even than atropine, it also forms less compact crystals. Its fusing
point is 149.6 deg. F. I have not yet succeeded in crystallizing any of
its more simple salts. The double platinum salt melts at 392 deg. F., with
decomposition. The double gold salt, which has been described above,
does not melt in boiling water, and its aqueous solution is reduced
neither by boiling nor by long exposure to light. By leaving the hot
saturated solution to cool it does not cloud, but the double salt
separates pretty rapidly in the form of plates.
One liter of water containing 10 cubic centimeters of hydrochloric acid
at 1.19 deg. dissolves 65 centigrammes of the salt at 146 deg. F.
These characteristics allow us to differentiate atropine and
hyoscyamine, the reactions of which are almost identical, as will be
seen from the following table, which shows the action of weak solutions
of the acids named on the hydrochlorates of the bases:
_Reagents_. _Hyoscyamine_. _Atropine_.
Picric acid. An oil solidifying Crystalline precipitate.
immediately into
tabular crystals.


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